BIOPHARMACEUTICAL SCIENCE
| 1101 | 1501 | 2110 | 2510 | 3101 | 3151 | 3350 | 3501 | 3551 | 3750 |
| 3901 | 3902 | 4006 | 4019 | 4101 | 4102 | 4103 | 4104 | 4111 | 4121 |
| 4123 | 4125 | 4126 | 4127 | 4129 | 4131 | 4501 | 4503 | 4504 | 4511 |
| 4521 | 4523 | 4525 | 4526 | 4527 | 4900 | 4901 | 4902 | 4904 |
| BPS1101 | Drugs 101 | (3,0,0) 3 cr. |
| Drug history, discovery and use. Origins of disease, drug function, side effects and safety. Toxicology, pain relief, cold medications, performance-enhancing drugs for sports, antibiotics and cancer chemotherapy. | ||
| This course cannot count as a science optional course, but may be used as an elective. | ||
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| BPS1501 | M茅dicaments 101 | (3,0,0) 3 cr. |
| L'histoire des m茅dicaments; d茅couverte et utilisation. Origine des maladies, d茅veloppement des m茅dicaments, interactions entre les m茅dicaments, effet et innocuit茅 des m茅dicaments. Toxicologie, analg茅siques, m茅dicaments contre le rhume, st茅ro茂des anabolisants, antibiotiques, chimioth茅rapie. | ||
| Ce cours ne peut pas 锚tre utilis茅 comme cours optionnel en sciences, mais il peut 锚tre utilis茅 comme cours au choix. | ||
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| BPS2110 | Introduction to Biopharmaceutical Sciences | (3,0,0) 3 cr. |
| Study of the properties and biological activity of therapeutic substances including pharmaceuticals, biologics, natural health products and nutraceuticals, and related issues of dosage forms, good manufacturing practices (GMP) and quality assurance. | ||
| Prerequisites: CHM1321, BIO1140. | ||
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| BPS2510 | Introduction aux sciences biopharmaceutiques | (3,0,0) 3 cr. |
| 脡tude des propri茅t茅s et de l'activit茅 biologique des substances th茅rapeutiques, telles que les produits pharmaceutiques et biologiques, les produits de sant茅 naturels et les produits nutraceutiques, ainsi que les aspects reli茅s aux formes posologiques, les bonnes pratiques de fabrication (BPF) et le contr么le de qualit茅. | ||
| Pr茅alables : CHM1721, BIO1540. | ||
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| BPS3101 | Genomics | (3,0,0) 3 cr. |
| Broad introduction to genomics research, with strong emphasis on comparative genomics. Structure and organization of prokaryotic and eukaryotic genomes; gene mapping and DNA sequencing technologies; systematic methods for identification of gene function; drug discovery; proteomics. Introduction to bioinformatics and human genomic project. | ||
| Prerequisite: BIO2133. | ||
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| BPS3151 | Molecular Biology Laboratory | (0,0,6) 3 cr. |
| Introduction to basic techniques in molecular biology and their application in biotechnology. | ||
| Prerequisite or corequisite: BIO3170. The courses BIO3151, BCH3356, BPS3151 cannot be combined for credits. | ||
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| BPS3350 | Transition Metal Chemistry | (3,0,0) 3 cr. |
| Coordination complexes, ligand field theory, magnetic and spectroscopic properties, stereochemistry, optical and stereoisomerism, reactions of complexes: substitution, electron transfer, isomerization, photochemistry. | ||
| Prerequisites: CHM2120, CHM2311, (CHM2131 or CHM2132). The courses BPS3350, CHM3350 cannot be combined for credits. This course cannot be taken by students in the Honours or the Major in Chemistry. | ||
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| BPS3501 | La g茅nomique | (3,0,0) 3 cr. |
| Introduction g茅n茅rale 脿 la recherche en g茅nomique mettant l'accent sur la g茅nomique comparative. Structure et organisation du g茅nome des procaryotes et eucaryotes; cartographie des g猫nes et technologie de s茅quen莽age d'ADN, m茅thodes syst茅matiques utilis茅es pour l'identification de la fonction des g猫nes, d茅couverte de drogues, prot茅omique. Introduction 脿 la bioinformatique et au projet du g茅nome humain. | ||
| Pr茅alable : BIO2533. | ||
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| BPS3551 | Laboratoire de biologie mol茅culaire | (0,0,6) 3 cr. |
| Introduction aux techniques de base en biologie mol茅culaire et leur utilisation en biotechnologie. | ||
| Pr茅alable ou concomitant: BIO3570. Les cours BIO3551, BCH3756, BPS3551 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. | ||
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| BPS3750 | Chimie des m茅taux de transition | (3,0,0) 3 cr. |
| Complexes de coordination, th茅orie du champ de ligands, propri茅t茅s magn茅tiques et spectroscopiques, st茅r茅ochimie, isom茅ries optique et g茅om茅trique, r茅actions des complexes : substitutions, transferts d'茅lectrons, isom茅risation, photochimie. | ||
| Pr茅alables : CHM2520, CHM2711, (CHM2531 ou CHM2532). Les cours BPS3750, CHM3750 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. Ce cours ne peut 锚tre suivi par des 茅tudiants et 茅tudiantes inscrits 脿 la majeure ou au sp茅cialis茅 approfondi en chimie. | ||
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| BPS3901 | Stage coop I / CO-OP Work Term I | 3 cr. |
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| BPS3902 | Stage coop II / CO-OP Work Term II | 3 cr. |
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| BPS4006 | Projet de recherche / Honours Project | (0,0,9) 9 cr. |
| A two session research project that will be completed under the supervision of a designated professor. Students will present their results in a seminar or as a poster and submit a written report. Un projet de recherche d'une dur茅e de deux sessions compl茅t茅 sous la direction d'un professeur d茅sign茅. Les 茅tudiants pr茅senteront leurs r茅sultats sous forme de pr茅sentation orale ou d'affiche et r茅digeront un rapport de projet. |
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| Corequisite: BPS4900. For students in their last full year of the Biopharmaceutical Science program who have maintained a minimum overall CGPA of 6.0 or have a GPA of at least 6.0 on their last completed 54 credits or permission of the Director of the BPS program. Students enrolled in the Co-op program should take BPS4006 during their last full year of studies. Concomitant : BPS4900. Pour 茅tudiants et 茅tudiantes dans leur derni猫re ann茅e compl猫te du programme en Sciences biopharmaceutiques qui ont conserv茅 une MPC minimale de 6.0 ou une MP minimale de 6.0 sur les derniers 54 cr茅dits compl茅t茅s ou la permission du Directeur du programme BPS. Les 茅tudiants inscrits au r茅gime coop doivent prendre BPS4006 durant leur derni猫re ann茅e compl猫te d'茅tudes. |
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| BPS4019 | Projet de recherche / Honours Project | 6 cr. |
| A one session research project that will be completed under the supervision of a designated professor. Students will present their results in a seminar or as a poster and submit a written report. Un projet de recherche d'une dur茅e d'une session compl茅t茅 sous la supervision d'un professeur d茅sign茅. Les 茅tudiants pr茅senteront leurs r茅sultats sous forme de pr茅sentation orale ou d'affiche et r茅digeront un rapport de projet. |
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| Corequisite : BPS4900. For students in their last year of the Biopharmaceutical Science program who have maintained a minimum overall CGPA of 6.0 or have a GPA of at least 6.0 on their last completed 54 credits or permission from the Director of the BPS program. Students interested in completing an Honours project should take BPS4006 that lasts two sessions. BPS4019 aims to accommodate students who for exceptional reasons can not complete an Honours project over two consecutive sessions. Any registration to BPS4019 must be approved by the Director of the BPS program. Concomitant : BPS4900. Pour 茅tudiants et 茅tudiantes dans leur derni猫re ann茅e du programme en Sciences biopharmaceutiques qui ont conserv茅 une MPC minimale de 6.0 ou une MP minimale de 6.0 sur les derniers 54 cr茅dits compl茅t茅s ou la permission du directeur du programme BPS. Les 茅tudiants int茅ress茅s 脿 compl茅ter un projet de recherche devraient s'inscrire 脿 BPS4006 qui est d'une dur茅e de deux sessions. BPS4019 vise 脿 accommoder les 茅tudiants qui pour des raisons exceptionnelles ne peuvent pas compl茅ter un projet de recherche d'une dur茅e de deux sessions cons茅cutives. Toute inscription 脿 BPS4019 doit 锚tre pr茅alablement approuv茅e par le directeur du programme BPS. |
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| BPS4101 | Human Genome Structure and Function | (3,0,0) 3 cr. |
| First half of course will focus on human chromosomes, chromatin structure, genome organization, genetic and physical mapping and the human genome project. Second half will examine the genome at the level of the gene, and covers gene structure, gene regulation, gene splicing, mRNA transport and protein synthesis. Examples of inherited and acquired genetic diseases will be discussed. | ||
| Prerequisite: BCH3170 or BIO3170. The courses BPS4101, BCH4101 cannot be combined for credits. | ||
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| BPS4102 | Pharmaceuticals: Federal and International Regulations | (3,0,0) 3 cr. |
| Introduction to Canadian Acts, Regulations and Guidelines pertaining to registration of agents affecting humans, animals and/or the environment. Comparative information on international trends and regulations. Basic knowledge for preparing submission packages in support of registration of new biopharmaceutical products. Discussion on the submission review process undertaken by Canadian regulatory agencies in carrying out detailed risk assessment of new products. Not necessarily offered every year. | ||
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| BPS4103 | Selected topics in Biopharmaceutical Sciences | (3,0,0) 3 cr. |
| Lectures and seminars on selected topics in Biopharmaceutical Sciences. | ||
| Prerequisite: 15 credits in science at the 3000 level and above. | ||
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| BPS4104 | Bioinformatics Laboratory | (1,0,4) 3 cr. |
| Principles of organization, retrieval, manipulation, and analysis of molecular data in genomics, proteomics and transcriptomics. Hands-on analysis of these data to solve biological questions using quantitative and computational methods. | ||
| Prerequisites: BPS3101, BIO3102. | ||
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| BPS4111 | Directed Studies in Biopharmaceutical Sciences | 3 cr. |
| This course involves a major literature review of a topic of current interest in the field. Upon completion of the written review the students will present and defend the key findings in a seminar. Students will choose their review subject in consultation with a professor assigned by the Program Director. For students in the last year of the Biopharmaceutical Science Honours program. | ||
| The courses BPS4111, BPS4006, BPS4019 cannot be combined for credits. | ||
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| BPS4121 | Biosynthesis and Natural Product Derived Medicines | (3,0,0) 3 cr. |
| A study of the major biosynthetic pathways used by plants, bacteria and animals to synthesize the major families of secondary metabolites including fatty acids, phenolics, lignans, terpenes, steroids and alkaloids. The traditional use of certain natural products themselves as medicines and their value as lead compound for new drugs will be discussed. The synthesis of the natural products themselves or that of useful derivatives will also be studied. | ||
| Prerequisite: CHM3120. The courses BPS4121, BPS4123 cannot be combined for credits. | ||
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| BPS4123 | Phytomedicines and Natural Product Drugs | (3,0,0) 3 cr. |
| Ethnopharmacology and the discovery and development of natural product drugs. Phytochemistry and mode of action of major phytomedicines. Challenges in quality control and regulation. Pharmaceuticals derived from natural products. | ||
| Prerequisites: CHM2120, BIO2137. The courses BPS4123, BPS4121 cannot be combined for credits. | ||
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| BPS4125 | Medicinal Chemistry | (3,0,0) 3 cr. |
| Drug design, discovery and synthesis, including structure-activity relationships, modes of action and recent therapeutic progress. Process chemistry including environmental considerations. | ||
| Prerequisite: CHM3120. The courses BPS4125, CHM4123 cannot be combined for credits. | ||
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| BPS4126 | Synthetic and Medicinal Chemistry Laboratory | (0,0,6) 3 cr. |
| The laboratory program will expose students to current methods and techniques used in the synthesis of pharmaceutical synthesis of pharmaceuticals and specialty chemicals. These include combinatorial chemistry, transition metal coupling reactions, enzyme mediated resolutions and complex carbohydrate synthesis. Products will be analyzed by modern spectroscopic methods for chemical purity and some will be tested in several biological screens. | ||
| Prerequisite: CHM3126. | ||
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| BPS4127 | Advanced Techniques in Biosciences | (0,0,6) 3 cr. |
| This laboratory course will expose students to advanced methods and techniques in biochemistry, molecular biology and cell biology. The course aims to allow a student to conduct a project involving the isolation, cloning, and expression of a gene. Gene function will be tested using biochemical and cellular assay systems. | ||
| Prerequisite: BCH3356 or BIO3151. Priority given to students in the 4th year of the Biochemistry, Biology or Biopharmaceutical Science programs who are not completing an honours research project. | ||
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| BPS4129 | Advanced Chemical Biology | (3,0,0) 3 cr. |
| This course focuses on chemical approaches to solving problems in molecular and cellular biology. Emphasis will be placed on multidisciplinary approaches to understand biological pathways and biological systems. Recent advances in chemical tool development for systems biology will be highlighted. Approaches to target selection for chemical intervention will also be covered. Topics include: chemical approaches to genomics and proteomics; protein design and engineering; chemistry in cellular imaging; chemistry in biotechnology; chemical genetics; rational and combinatorial approaches to pathway intervention; metabolic engineering. | ||
| Prerequisites: BCH2333, (CHM2131 or CHM2132). Corequisites: (CHM3120, BCH3170) or BIO3170. | ||
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| BPS4131 | Advanced Biopharmaceutical Science | (3,0,0) 3 cr. |
| Biopharmaceutics including pharmacokinetics, drug interactions, and emerging topics such as aptamers and metabolomics. | ||
| Prerequisite: BCH2333. | ||
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| BPS4501 | Structure et fonction du g茅nome humain | (3,0,0) 3 cr. |
| La premi猫re moiti茅 du cours se concentre sur les chromosomes humains, la structure de la chromatine, l'organisation du g茅nome, la cartographie g茅n茅tique et physique et le projet du g茅nome humain. La deuxi猫me moiti茅 du cours examine le g茅nome au niveau du g猫ne, et couvre la structure des g猫nes, la r茅gulation des g猫nes, l'茅pissage des g猫nes, le transport de l'ARNm et la synth猫se des prot茅ines. Des exemples de maladies g茅n茅tiques h茅rit茅es et acquises seront discut茅s. | ||
| Pr茅alables : BCH3570 ou BIO3570. Les cours BCH4501, BPS4501 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. | ||
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| BPS4503 | Th猫mes choisis en sciences biopharmaceutiques | (3,0,0) 3 cr. |
| Cours et s茅minaires sur un sujet choisi en sciences biopharmaceutiques. | ||
| Pr茅alable : 15 cr茅dits en science de niveau 3000 et plus. | ||
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| BPS4504 | Laboratoire de bioinformatique | (1,0,4) 3 cr. |
| Principes d'organisation, de r茅cup茅ration, de manipulation et d'analyse de donn茅es mol茅culaires en g茅nomique, prot茅omique et transcriptomique. Analyses pratiques de ces donn茅es pour r茅soudre des questions biologiques en utilisant des m茅thodes quantitatives et computationnelles. | ||
| Pr茅alables : BPS3501, BIO3502. | ||
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| BPS4511 | 脡tudes dirig茅es en sciences biopharmaceutiques | 3 cr. |
| Revue de la litt茅rature sur un sujet d'actualit茅 dans le domaine. Les r茅sultats de l'茅tude sont pr茅sent茅s lors d'un s茅minaire. Les 茅tudiants choisissent le sujet de l'茅tude en consultation avec un professeur assign茅 par le directeur du programme. Pour les 茅tudiants dans leur derni猫re ann茅e du B.Sc. sp茅cialis茅 en sciences biopharmaceutiques. | ||
| Les cours BPS4511, BPS4006, BPS4019 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. | ||
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| BPS4521 | Biosynth猫se de m茅dicaments d茅riv茅s de plantes m茅dicinales | (3,0,0) 3 cr. |
| L'茅tude des voies biosynth茅tiques utilis茅es par les plantes, les bact茅ries et les animaux pour la synth猫se d'importantes familles de m茅tabolites secondaires, incluant les acides gras, les ph茅nols, lignanes, terp猫nes, st茅ro茂des et alkalo茂des. L'usage traditionel de certains produits naturels comme m茅dicaments et leurs valeurs comme substances de d茅part pour la synth猫se de nouveaux m茅dicaments seront 茅tudi茅s. La synth猫se de produits naturels ou de leurs d茅riv茅s sera aussi 茅tudi茅e. | ||
| Pr茅alable : CHM3520. Les cours BPS4521, BPS4523 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. | ||
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| BPS4523 | Produits naturels et phytom茅dicaments | (3,0,0) 3 cr. |
| Ethnopharmacologie; d茅couverte et d茅veloppements de m茅dicaments provenant de produits naturels. Phytochimie et mode d'action des principaux phytom茅dicaments. D茅fis dans le contr么le de qualit茅 et la r猫glementation. Produits pharmaceutiques d茅riv茅s de compos茅s naturels. | ||
| Pr茅alables : CHM2520, BIO2537. Les cours BPS4521, BPS4523 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. | ||
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| BPS4525 | Chimie m茅dicinale | (3,0,0) 3 cr. |
| Conception, d茅couverte et synth猫se des m茅dicaments incluant la relation entre la structure et l'activit茅, les modes d'action ainsi que les progr猫s r茅cents en recherche th茅rapeutique. Chimie des proc茅d茅s, incluant des consid茅rations environnementales. | ||
| Pr茅alable : CHM3520. Les cours CHM4523, BPS4525 ne peuvent 锚tre combin茅s pour l'obtention de cr茅dits. | ||
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| BPS4526 | Laboratoire de chimie m茅dicinale et synth猫se organique | (0,0,6) 3 cr. |
| Le programme du laboratoire exposera les 茅tudiants aux diff茅rentes m茅thodes et techniques utilis茅es en synth猫se organique. Ceci inclut la chimie combinatoire, la synth猫se des hydrates de carbone complexes, r茅solution enzymatique et r茅action de couplage utilisant les m茅taux de transition. Les produits seront caract茅ris茅s par spectroscopie moderne. (RMN, IR, etc.) et quelques-uns seront soumis 脿 plusieurs tests biologiques. | ||
| Pr茅alable : CHM3526. | ||
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| BPS4527 | Techniques avanc茅es en biosciences | (0,0,6) 3 cr. |
| Les 茅tudiants participant 脿 ce cours seront expos茅s 脿 des m茅thodes et des techniques avanc茅es en biochimie, en biologie mol茅culaire et en biologie cellulaire. L'emphase sera mise sur le design exp茅rimental et sur l'usage appropri茅 de contr么les. Le but du cours est de permettre 脿 l'茅tudiant de mener 脿 bien un projet impliquant l'isolation, le clonage et l'expression d'un g猫ne. La fonction du g猫ne sera 茅tudi茅e en utilisant des syst猫mes d'essais biochimiques et cellulaires. | ||
| Pr茅alable : BCH3756 ou BIO3551. Priorit茅 accord茅e aux 茅tudiants et 茅tudiantes de 4i猫me ann茅e des programmes de biochimie, biologie ou Sciences biopharmaceutiques qui ne sont pas inscrits au projet de recherche | ||
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| BPS4900 | S茅minaire / Seminar | 3 cr. |
| Presentations by students on recent trends in various aspects of biopharmaceutical sciences will be discussed. For students in their last year of the Biopharmaceutical Science Honours program only. | ||
| Previously BPS4000. | ||
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| BPS4901 | Stage coop III / CO-OP Work Term III | 3 cr. |
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| BPS4902 | Stage coop IV / CO-OP Work Term IV | 3 cr. |
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| BPS4904 | Stage coop V / CO-OP Work Term V | 3 cr. |
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